A Brand
New Addition To Mesothelioma Treatment By K James
Sirolimus - Mesothelioma treatment
improved with addition to Sirolimus treatment. This is wonderful news
for mesothelioma patient because of its anti-proliferative effects;
sirolimus is now being looked at for the treatment of malignant
mesothelioma and a number of other cancers.
After being diagnosed with mesothelioma it is natural to experience a
whirlwind of emotions. This lethal disease can definitely turn your
life upside down, but rests assure that researchers are working night
and day to find a cure for you!
Researchers at the Boston women’s hospital report that the immune
suppressant drug called Sirlimus is an effective mesothelioma
treatment. According to the researchers working at Brigham and
Women’s Hospital in Boston they saw greater success when using
sirolimus along with cisplatin than they did when using cisplatin
alone.What Is Sirolimus?
Sirolimus also known as rapamycin is an immunosuppressant drug which is
typically used to prevent rejection of organ transplantations
especially in kidney transplants. Sirolimus has an anti-proliferative
effect which makes it an effective treatment option for
mesothelioma.Benefits of Sirolimus
It is believed that the benefits of sirolimus could make it easier to
treat certain cancers. Sirolimus acts as an inhibitor in the
development of certain proteins that affects the cell survival and cell
growth among others. The researchers also stated that upon observation
of combination of sirolimus and cisplatin “Sirolimus appears to
enhance the cytotoxicity of cisplatin in malignant pleural mesothelioma
cell lines through the mammalian target rapamycin pathway. These
results provide a basis for the clinical evaluation of combined
sirolimus and cisplatin chemotherapy in malignant pleural
mesothelioma.”
Precautions & Warnings When Taking Sirolimus
According to research, before taking sirolimus you should follow these
guidelines:
Sirolimus - Mesothelioma
treatment improved
*Let your doctor know if your are
allergic to any medication
* Give your doctor a list of medication
(prescription or non prescription) including vitamins nutritional
supplements, herbal products and make sure you let your doctor know if
you are taking amphotericin B, antifungals, ketoconazole,
bromocriptine, cimetidine, HIV protease inhibitors, seizure medication,
Phenobarbital, metoclopramide, rifabutin, verapamil or any other
medication. Your doctor will need this information to prescribe
appropriate dosage of your medication or to monitor for any side
effects.
* Let your doctor know if you are
pregnant, plan to become pregnant or breastfeeding.
* Tell your doctor if you suffer from
high cholesterol or triglycerides of liver disease.t is best to
disclose any health conditions and medications to your doctor before
taking sirolimus.
Are There Any Side Effects Caused By
Sirolimus?
Possible side effects of Sirolimus are:
* Headache
* Constipation
* Back pain
* Diarrhea
* Weight loss
* Fever
* Weakness
* Vomiting
* Stomach pain
There are other serious side effects
which are uncommon, but if you experience pale skin, shortness of
breathe of unusual bleeding or bruising you should call your doctor
immediately.
The most frequently recommended treatments for pleural mesothelioma
patients has been chemotherapy, radiation therapy and surgery or a
combination of two or more of these types of treatment and medication.
But with sirolimus, this new addition will significantly improve the
lives of mesothelioma patients.
These clinical researches are making advancements in the treatment of
mesothelioma. Patients suffering from mesothelioma are volunteering to
receive the newest development in mesothelioma treatment in the hopes
of finding a cure for this disease. We hope that one day there will be
a cure for this lethal disease.
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